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14-3-3 Protein in the CSF of Patients with Rapidly Progressive Dementia Neurol 61:354-357, Huang,N.,et al, 2003 See this aricle in Pubmed Article Abstract The detection of 14-3-3 protein in CSF is a useful in vivo diagnostic test for CJD and, when used in the appropriate clinical context, shows a good correlation to CJD. The presence of the 14-3-3 protein in the CSF reinforces the CJD clinical diagnosis but may not be able to differentiate CJD from other causes of rapidly progressive dementia in everyday clinical practice.

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